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D6

ActiveQuality: ****

Rerolls item pedestals into different items. Isaac's signature item and one of the most consistently useful active items in the game.

PvE Rating

★★★★★

5/5

Strengths

  • +Complete control over item quality.
  • +Works on any item pedestal in the game.
  • +Consistent value every single floor.

Weaknesses

  • -Rerolls are random; can reroll into worse items.
  • -Limited charges without Battery items.
  • -Takes the active item slot.

Pro Tips

  • 1Reroll low-quality Treasure Room items for better options.
  • 2Save charges for Boss Room drops if the current item is decent.
  • 3Combine with Battery items for multiple rerolls per floor.