Isaac
Easy
The default character with balanced stats. Starts with The D6 after unlocking it, allowing rerolls of item pedestals for better options.
Health
3 Red Heart Containers
Starting Item
The D6
PvE Rating
★★★★★
5/5
Strengths
- +D6 allows control over item quality across the entire run.
- +Balanced stats make him adaptable to any build.
- +No gimmicks means straightforward gameplay for learning.
Weaknesses
- -D6 must be unlocked first by defeating Mom's Heart.
- -No innate damage or survivability advantage.
- -Relies heavily on finding good items through rerolls.
Pro Tips
- 1Use the D6 on low-quality items in Treasure Rooms to reroll into something stronger.
- 2Save D6 charges for Boss Room item drops if your Treasure Room item is already decent.
- 3Combine with Battery items to get multiple rerolls per floor.